Our writing is based on three premises. First, life sciences students are motivated by and respond well to actual data related to real life sciences problems. Second, the ultimate goal of calculus in the life sciences primarily involves modeling living systems with difference and differential equations. Understanding the concepts of derivative and integral are crucial, but the ability to compute a large array of derivatives and integrals is of secondary importance. Third, the depth of calculus for life sciences students should be comparable to that of the traditional physics and engineering calculus course; else life sciences students will be short changed and their faculty will advise them to take the 'best' (engineering) course.

Our writing is based on three premises. First, life sciences students are motivated by and respond well to actual data related to real life sciences problems. Second, the ultimate goal of calculus in the life sciences primarily involves modeling living systems with difference and differential equations. Understanding the concepts of derivative and integral are crucial, but the ability to compute a large array of derivatives and integrals is of secondary importance. Third, the depth of calculus for life sciences students should be comparable to that of the traditional physics and engineering calculus course; else life sciences students will be short changed and their faculty will advise them to take the 'best' (engineering) course.

In our text, mathematical modeling and difference and differential equations lead, closely follow, and extend the elements of calculus. Chapter one introduces mathematical modeling in which students write descriptions of some observed processes and from these descriptions derive first order linear difference equations whose solutions can be compared with the observed data. In chapters in which the derivatives of algebraic, exponential, or trigonometric functions are defined, biologically motivated differential equations and their solutions are included. The chapter on partial derivatives includes a section on the diffusion partial differential equation. There are two chapters on non-linear difference equations and on systems of two difference equations and two chapters on differential equations and on systems of differential equation.

This textbook covers calculus of a single variable, suitable for a year-long (or two-semester) course. Chapters 1-5 cover Calculus I, while Chapters 6-9 cover Calculus II. The book is designed for students who have completed courses in high-school algebra, geometry, and trigonometry. Though designed for college students, it could also be used in high schools. The traditional topics are covered, but the old idea of an infinitesimal is resurrected, owing to its usefulness (especially in the sciences).

This book is an approachable introduction to calculus with applications to biology and environmental science. For example, one application in the book is determining the volume of earth moved in the 1959 earthquake that created Quake Lake. Another application uses differential equations to model various biological examples, including moose and wolf populations at Isle Royale National Park, ranavirus in amphibians, and competing species of protozoa. The text focuses on intuitive understanding of concepts, but still covers most of the algebra and calculations common in a survey of calculus course.

This textbook, or really a “coursebook” for a college freshman-level class, has been updated for Spring 2014 and provides an introduction to programming and problem solving using both Matlab and Mathcad. We provide a balanced selection of introductory exercises and real-world problems (i.e. no “contrived” problems). We include many examples and screenshots to guide the reader. We assume no prior knowledge of Matlab or Mathcad.