By the end of this section, you will be able to do the following:
Explain the different ways natural selection can shape populations
Describe how these different forces can lead to different outcomes in terms of the population variation
By the end of this section, you will be able to do the following:
Define population genetics and describe how scientists use population genetics in studying population evolution
Define the Hardy-Weinberg principle and discuss its importance
By the end of this section, you will be able to do the following:
Describe the different types of variation in a population
Explain why only natural selection can act upon heritable variation
Describe genetic drift and the bottleneck effect
Explain how each evolutionary force can influence a population's allele frequencies
By the end of this section, you will be able to do the following:
Explain pharmacogenomics
Define polygenic
By the end of this section, you will be able to do the following:
Describe gel electrophoresis
Explain molecular and reproductive cloning
Describe biotechnology uses in medicine and agriculture
By the end of this section, you will be able to do the following:
Explain systems biology
Describe a proteome
Define protein signature
By the end of this section, you will be able to do the following:
Define genomics
Describe genetic and physical maps
Describe genomic mapping methods
By the end of this section, you will be able to do the following:
Describe three types of sequencing
Define whole-genome sequencing
By the end of this section, you will be able to do the following:
Explain how the structure of DNA reveals the replication process
Describe the Meselson and Stahl experiments
By the end of this section, you will be able to do the following:
Discuss the different types of mutations in DNA
Explain DNA repair mechanisms
By the end of this section, you will be able to do the following:
Discuss the similarities and differences between DNA replication in eukaryotes and prokaryotes
State the role of telomerase in DNA replication
By the end of this section, you will be able to do the following:
Explain the process of DNA replication in prokaryotes
Discuss the role of different enzymes and proteins in supporting this process
By the end of this section, you will be able to do the following:
Describe the structure of DNA
Explain the Sanger method of DNA sequencing
Discuss the similarities and differences between eukaryotic and prokaryotic DNA
By the end of this section, you will be able to do the following:
Explain transformation of DNA
Describe the key experiments that helped identify that DNA is the genetic material
State and explain Chargaff’s rules
By the end of this section, you will be able to do the following:
Describe how changes to gene expression can cause cancer
Explain how changes to gene expression at different levels can disrupt the cell cycle
Discuss how understanding regulation of gene expression can lead to better drug design
By the end of this section, you will be able to do the following:
Explain how chromatin remodeling controls transcriptional access
Describe how access to DNA is controlled by histone modification
Describe how DNA methylation is related to epigenetic gene changes
By the end of this section, you will be able to do the following:
Understand RNA splicing and explain its role in regulating gene expression
Describe the importance of RNA stability in gene regulation
