The Biology I Course was developed through the Ohio Department of Higher Education OER Innovation Grant. The course is part of the Ohio Transfer Assurance Guides and is also named OSC003. This work was completed and the course was posted in October 2019. For more information about credit transfer between Ohio colleges and universities, please visit: www.ohiohighered.org/transfer.Team LeadCathy Sistilli                                         Eastern Gateway Community CollegeContent ContributorsLisa Aschemeier                                 Northwest State Community CollegeShaun Blevins                                     Rhodes State CollegeRachel Detraz                                     Edison State Community College                                     Sara Finch                                          Sinclair Community CollegeWendy Gagliano                                 Clark State Community College AJ Snow                                             University of Akron Wayne CollegeLibrarianAmanda Rinehart                               Ohio State UniversityReview TeamJessica Hall                                        Ohio Dominican UniversitySanhita Gupta                                    Kent State UniversityErica Mersfelder                                 Sinclair Community College

Meiosis is the process of cell division that produces haploid gametes.  In sexual reproduction haploid gametes combine through fertilization to form a genetically recombined diploid zygote.  Meiosis includes two successive divisions and processes such as crossing over and independent assortment that increase genetic variability in gametes produced.  Life cycles detail the events between meiosis and fertilization that vary for different multicellular organisms.

By the end of this section, you will be able to do the following:

Explain that meiosis and sexual reproduction are highly evolved traits
Identify variation among offspring as a potential evolutionary advantage of sexual reproduction
Describe the three different life-cycle types among sexually reproducing multicellular organisms.

By the end of this section, you will be able to do the following:

Describe the behavior of chromosomes during meiosis, and the differences between the first and second meiotic divisions
Describe the cellular events that take place during meiosis
Explain the differences between meiosis and mitosis
Explain the mechanisms within the meiotic process that produce genetic variation among the haploid gametes

By the end of this section, you will be able to do the following:

Explain Mendel’s law of segregation and independent assortment in terms of genetics and the events of meiosis
Use the forked-line method and the probability rules to calculate the probability of genotypes and phenotypes from multiple gene crosses
Explain the effect of linkage and recombination on gamete genotypes
Explain the phenotypic outcomes of epistatic effects between genes

By the end of this section, you will be able to do the following:

Discuss Sutton’s Chromosomal Theory of Inheritance
Describe genetic linkage
Explain the process of homologous recombination, or crossing over
Describe chromosome creation
Calculate the distances between three genes on a chromosome using a three-point test cross

Biology is designed for multi-semester biology courses for science majors. It is grounded on an evolutionary basis and includes exciting features that highlight careers in the biological sciences and everyday applications of the concepts at hand. To meet the needs of today’s instructors and students, some content has been strategically condensed while maintaining the overall scope and coverage of traditional texts for this course. Instructors can customize the book, adapting it to the approach that works best in their classroom. Biology also includes an innovative art program that incorporates critical thinking and clicker questions to help students understand—and apply—key concepts.